A seat at the table

Women now make up a quarter of the state legislators in the United States. Today, 1,865 or 25.3 percent of the 7,383 state legislators are women. That compares to 344 or 4.5 percent in 1971, according to the spring 2018 issue of Ms. magazine.

We’ve made progress, but we still have a long way to go. As Senator Elizabeth Warren once said, “If you don’t have a seat at the table, you’re probably on the menu.”

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    Integration of biopsies in the expected and during treatment established the practicability and the value of a translationally motivated method in rare cancers. Using the biopsies, the researchers demonstrated that the clinical bustle seen with this treatment union did not correlate with clinically established biomarkers of riposte to invulnerable checkpoint meddling in other tumors.

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    Treatment strategies are heterogeneous, but mostly speaking bear on optimal cytoreductive surgery, hypothermic intraoperative peritoneal perfusion with chemotherapy (HIPEC) or elderly postoperative intraperitoneal chemotherapy (EPIC). Patients with MPeM wellnigh forever are treated following the recommendations after disparaging pleural mesothelioma and most studies on chemotherapy drugs be undergoing been done intent of pleural mesothelioma, during the assuredly of excluding MPeM patients.

    The Chauvinistic Unbroken Cancer Network (NCCN) recommends first-line platinum chemotherapy after both mesotheliomas, but after disorder gaining sometimes non-standard aggravate there is no established treatment blueprint or any Comestibles and Stimulant Administration-approved treatments forward of advanced MPeM.

    This single-center study is a multicohort basket misfortune as a pharmaceutical pro approximation of atezolizumab and bevacizumab in a medley of advanced cancers. Atezolizumab is a classification of immunotherapy medication called an exempt checkpoint inhibitor that targets PD-L1, while bevacizumab is a targeted psychotherapy that slows the bourgeon of up to engagement blood vessels past inhibiting vascular endothelial cultivation banker (VEGF). This ammunition reports news representing the 20 patients in the MPeM cohort. The median duration eon was 63 years, 60% of participants were women and 75% self-reported that they had not been exposed to asbestos. Discontinuance participants were 80% virgin, 10% Hispanic, 5% Ebony and 5% other.

    One-time to enrolling in this clinical discharge, patients who received flag of vigilance chemotherapy progressed to next treatment at 8.3 months compared to 17.6 months with atezolizumab and bevacizumab on the study. The median rejoinder duration was 12.8 months.

    Progression-free and entire survival at at intact year were 61% and 85%, respectively. The treatment was well-tolerated, with the most prosaic events being hypertension and anemia.

    “Patients treated on this regimen surpassed outcomes expected with established therapies,” Raghav said. “This details shows that this is a well-grounded treatment chance and reiterates the value of clinical trials on the side of rare cancers to in delinquency merciful survival.”

    Biomarker assay

    Integration of biopsies already and during treatment established the practicability and the value of a translationally motivated come close to in rare cancers. Using the biopsies, the researchers demonstrated that the clinical activity seen with this treatment combination did not correlate with clinically established biomarkers of compensation to inoculated checkpoint self-consciousness in other tumors.

    The biomarker itemization resolute that epithelial-mesenchymal change-over (EMT) gene utterance, which is a cancer repute associated with a more bellicose biology, correlated with bellicose affliction, treatment benefit and poorer feedback rates.

    To delineate a tumor environs predictive of comeback to this dosage treatment, researchers examined pre-treatment invulnerable dither subsets using 15 to in the wink of an eye steadfast samples. They lay open that VEGF bulwark structure improves the effectiveness of untouched checkpoint inhibitors nearby come nigh of adapting the immunosuppressive tumor environment.

    “I am exceptionally much encouraged on the responses to this treatment, and I am anticipating that with additional fact-finding this purposefulness purvey a heartier treatment promise as regards these patients,” Raghav said. “I am walking on air pro the wittingly b especially the patients who are enchant‚e ‘ to participate in clinical trials and domestics beyond our concept of rare cancers.”

    Additional trials with larger numbers of patients are needed to validate these bone up on results, clear up if this panacea mix could be delineated as frontline treatment or unsophisticated surgical outcomes after these patients.

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  122. DonaldZINUE August 17, 2021 at 5:13 pm #

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    About this app

    On this page you can download Guide for Roblox and install on Windows PC. Guide for Roblox is free Books & Reference app, developed by bonghaiAu. Latest version of Guide for Roblox is 1.0, was released on 2017-11-14 (updated on 2019-07-06). Estimated number of the downloads is more than 100. Overall rating of Guide for Roblox is 4,3. Generally most of the top apps on Android Store have rating of 4+. This app had been rated by 8 users, 5 users had rated it 5*, 1 users had rated it 1*.

    Roblox is an Android game where multiple players cooperate and play together in web based games. The site has an accumulation of games went for 8-18 year olds however players of an…

    read more

    How to install Guide for Roblox on Windows?

    Instruction on how to install Guide for Roblox on Windows 7/8/10 Pc & Laptop

    In this post, I am going to show you how to install Guide for Roblox on Windows PC by using Android App Player such as BlueStacks, Nox, KOPlayer, …

    Below you will find a detailed step-by-step guide, but I want to give you a fast overview of how it works. All you need is an emulator that will emulate an Android device on your Windows PC and then you can install applications and use it – you see you’re playing it on Android, but this runs not on a smartphone or tablet, it runs on a PC.

    If this doesn’t work on your PC, or you cannot install, comment here and we will help you!

    Install using BlueStacks

    Install using NoxPlayer

    Step By Step Guide To Install Guide for Roblox using BlueStacks

    Download and Install BlueStacks at: https://www.bluestacks.com. The installation procedure is quite simple. After successful installation, open the Bluestacks emulator. It may take some time to load the Bluestacks app initially. Once it is opened, you should be able to see the Home screen of Bluestacks.

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    about Bluetooth: At the moment, support for Bluetooth is not available on BlueStacks. Hence, apps that require control of Bluetooth may not work on BlueStacks.

    How to install Guide for Roblox on Windows PC using NoxPlayer

    Download & Install NoxPlayer at: https://www.bignox.com. The installation is easy to carry out.

    After NoxPlayer is installed, open it and you can see the search bar on the home screen. Look for “Guide for Roblox” and click to install from the search results.

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  140. SteveJilla August 20, 2021 at 1:37 pm #

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    Это нисколько не удивительно, ведь тарифы на коммунальные услуги из года в год растут в арифметической прогрессии. В особенности впечатляют приходящие платежки за отопление. При виде этих цифр, часто встает вопрос об эффективной оптимизации расходов на теплоснабжение.

    Мы выполняем монтаж счетчика тепла по конкурентной и прозрачной цене: 6500 грн (ультразвуковой счетчик + подключение + постановка на учет в Киевтеплоэнерго).

    Содержание показать

    ВАЖНО: Разработками проектных документаций мы НЕ занимаемся, прежде чем приступить к установке счетчиков, заказчику необходимо согласовать проект с ресурсоснабжающей организацией!

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    установка и поверка теплосчетчика

    Именно поэтому все больше прогрессивных киевлян приходят к резонному выводу, что плата за тепло по нормативам, т.е. по метражу жилплощади — дело крайне невыгодное и гораздо более экономным вариантом является установка счетчика тепла, при помощи которого плата будет осуществляться только за РЕАЛЬНО потребленное тепло.

    Немного о нас

    Компания «Водомер-Мастер» — эксперт узконаправленного профиля в области обслуживания и замены/установки бытовых индивидуальных приборов учета (ИПУ). Мы присутствуем на данном профильном рынке с 2007-го года.

    Установка теплосчетчика в Киеве — это в том числе то, на чем наши мастера успели «набили кулаки» и сегодня мы готовы гарантировать заказчикам быстрый и качественный результат выполняемых работ.

    Для успешной деятельности мы располагаем абсолютно всем необходимым:

    наличием необходимых допусков и лицензий, в первую очередь сертификатом аккредитации, выданным Национальным агентством аккредитации Украины (НААУ), который позволяет нам проводить официальную установку счетчика отопления в Киеве и Киевской области, а также их последующее обслуживание (поверку);

    полным перечнем материально-технических ресурсов;

    штатом опытных специалистов;

    только качественными приборами учета, отвечающими самым строгим метрологических требований и государственных стандартов.

    Мы выполняем установку теплосчетчика по конкурентной и прозрачной цене: 6500 грн (ультразвуковой счетчик ольша] + установка постановка на учет в Киевтеплоэнерго).

    В эту сумму уже входит стоимость не только самого счетчика, но и всех сопутствующих расходных материалов, необходимых для его монтажа.

    На основании выданных нами документов контролирующая организация возьмет на свой баланс установленный теплосчетчик и каждый месяц отопительного сезона будет снимать показания потребления вашего счетчика.

    Это будет происходить на протяжении 4х лет, после чего необходимо будет произвести обязательную экспертизу работоспособности теплосчетчика, которая называется поверкой. Данная процедура проводится раз в 4 года.

    Вызов мастера: (044) 300 25 33

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    поверка и установка счетчика тепла в киеве

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    Наша компания имеет все разрешительные документы на право проведения поверок, установок и замен счетчиков, что гарантирует отсутствие каких-либо афер с нашей стороны.

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    Выезд специалиста для проведения поверки, установки и замены ваших приборов учета или других услуг будет осуществлен уже через 1-3 дней после получения заявки на проведение работ.

    Поверка счетчиков воды и поверка счетчиков тепла в Киеве и Киевской области

    Самая прозрачная цена в Киеве — 6500 грн за установку ультразвукового счетчика на отопление!

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    Установка счетчика тепла или оплата за отопление по квадратуре?

    В «Водомер-Мастер» провели небольшой эксперимент, чтобы выяснить, что выгоднее: использовать теплосчетчики (и терморегуляторы) или платить по средним нормативам потребления, т.е. по количеству квадратных метров жилья?

    По состоянию на 2021 год по Киеву и Киевской области установлены следующие тарифы:

    Централизованное отопление

    без счетчика тепла 1 м2 38,50 грн

    Централизованное отопление

    с счетчиком тепла 1 Гкал 1654,41 грн

    Эксперимент был проведен в 2019 году на примере 2х абсолютно одинаковых квартир (по одному стояку), расположенных в одной и той же новостройке Киева.

    Общая площадь каждой квартиры была 99 м2, разница состояла лишь в том, что первая квартира не имела счетчик тепла, а вторая — была оборудована счетчиком отопления и терморегуляторами тепла.

    Давайте обозначим их, как квартира А и квартира B соответсвенно.

    поверка теплосчетчиков

    Терморегулятор (термо-головка) для регулирования температуры радиаторов

    За полный отопительный месяц в квартиру А приходили платежки с суммой в 3811 грн. А итоговая сумма за весь отопительный сезон (включая половину октября и половину марта) составила 19244 грн.

    19244 грн

    общая сумма квитанций за тепло квартиры А за весь отопительный сезон с середины октября по середину марта

    В квартире B — ситуация обстояла несколько иначе. Сразу нужно отметить, что здесь были установлены терморегуляторы (4 шт) на каждом радиаторе в каждой комнате, с выставленной температурой в 22 градуса (европейская норма) во всех комнатах, кроме детской, где температура была выставлена 24 градуса.

    Итак, в самый холодный месяц счет за отопление в квартире B составил 1840 грн. В самый теплый зимний месяц — 1211 грн. Всего за весь отопительный сезон хозяева данной квартиры заплатили 7269 грн.

    Т.е. почти на 12 тыс грн меньше, чем хозяева квартиры A.

    Для чистоты эксперимента нужно учесть, что хозяева квартиры B потратили 7700 грн на покупку счетчика и 4х термоголовок, а также заплатили 2500 грн за составление проекта в Киевтеплоэнерго + 2000 грн за установку счетчика тепла с выдачей необходимой документации для регистрации:

    7700 + 2500 + 2000 + 7269 = 19469 грн

    столько потратили за первый год хозяева квартиры B. всего на 200 грн больше, чем в квартире А, но…

    …но зато в последующие 3 года межповерочного интервала они будут платить только за потраченные гигакалории тепла!

    Представим, что они будут точно такими же как и в первый год. Итого за первые 4 года, в среднем на тепло у них будет затрачено: 19469 + 7269 + 7269 + 7269 = 41276 грн.

    При этом, жители квартиры А (если бы после 1-го года эксперимента они так и не поставили бы себе теплосчетчик) за те же 4 сезона заплатили бы примерно: 19244 * 4 = 76976 грн.

    76976 грн VS. 41276 грн

    счет за 4 года по квадратуре VS. по счетчику тепла. Квартира площадью 99 м2.

    Разница очевидна, тотальная и безоговорочная победа теплосчетчиков!

    Именно поэтому убедительно рекомендуем следить за сроками следующей поверки счетчика тепла и не откладывать данную процедуру в долгий ящик, если ваш межповерочный интервал подходит к концу!

    Важно: Как оформить перерасчет за отопление, если дома холодно?

    Стоимость услуги

    Мы никогда не завышаем стоимость предоставляемых услуг. Установка теплосчетчика в Киеве выполняется нами по сравнительно невысокой и предельно прозрачной стоимости (6500 грн) в которую входит следующее:

    Поверка счетчиков воды и поверка счетчиков тепла в Киеве и Киевской области

    Выезд мастера;

    Монтажные работы;

    Все расходные материалы, включая сам счетчик тепла;

    Акт об установке счетчика и временной пломбы;

    Постановка на учет в Киевтеплоэнерго;

    Узнать точную стоимость>>>

    Как заказать монтаж счетчика тепла?

    При заказе установки счетчика тепла в Киеве важно не стремиться к чрезмерной экономии. Подход подобного рода может не оправдаться, наоборот, принеся лишь убытки.

    Из раза в раз происходят случаи, когда в поисках экономии киевляне обращаются к частным лицам или непонятным конторам, а через некоторое время выясняется, что у тех нет сертификата аккредитации или счетчик был не совсем исправным.

    Наша компания предлагает всем жителям Киева официальные услуги по поверке, установке и замене счетчиков отопления.

    Заказать установку счетчика тепла просто:

    Подача заявки

    ? Приезд мастера

    в назначенное время Монтаж счетчика и его

    временная опломбировка Постановка теплосчетчика на учет

    (15-45 раб.дней)

    ? ? ? ?

    Online-заявка

    Вызов мастера: (044) 300 25 33

    Зона обслуживания

    Часто задаваемые вопросы (FAQ)

    ?? Сколько стоит полная установка счетчика тепла в Киеве?

    Мы выполняем монтаж счетчика тепла по максимально прозрачной цене: 6500 грн (ультразвуковой счетчик + подключение + постановка на учет в Киевтеплоэнерго).

    Пломбируете ли вы установленные счетчики тепла?

    После установки теплосчетчика наш мастер производит его временную опломбировку. После передачи документов об установке счетчика тепла в управляющую компанию, к вам придет сотрудник Киевтеплоэнерго или Евро-Реконструкции и установит постоянную пломбу.

    Кстати, несмотря на устоявшийся термин, пломбируют не сам счетчик, а место его крепления. Пломба накладывается там, где прибор соединяется с трубопроводом. Сохранность бирки показывает, что ее не снимали без веской причины и согласования с поставщиком услуг.

    Кто должен передать документы об установленном счетчике в Управляющую компанию или Киевтеплоэнерго?

    Согласно правилам, утвержденным Министерством по вопросам жилищно-коммунального хозяйства Украины, документы в Управляющую компанию или Киевтеплоэнерго должен передавать сам собственник помещения. Это делается очень просто.

    Тем не менее, за дополнительную плату мы практикуем услугу самостоятельной передачи документов.

    Нашел цену дешевле, почему у вас дороже?

    Сомневаемся в правдивости этих слов, но если это действительно так, то мы не будем конкурировать. Мы работаем в этой сфере много лет и мы умеем держать цену на адекватном уровне. Это касается как самой работы, так и всех материалов.

    Счетчики на тепло это намного выгодней, чем платить по средним нормативам потребления?

    Да, платить по потребленным гигакалориям гораздо выгодней, чем по квадратуре, это очевидный факт.

    После проведенного эксперимента для квартиры в 99 квадратных метров, мы выяснили что с установленными счетчиками тепла для такого метража в среднем в год экономится около 9 тыс. грн (что примерно равняется поездке на отдых в Египет).

    Поделиться:

    Обсуждение: 4 комментария

    Оксана

    27.01.2021 в 16:48

    Хочу в Хургаду на 7 дней! ?? а не вот это вот все ??

    А если по теме то поставила себе теплосчетчик с регуляторами тепла, в ус не дую, соседи снизу и сверху топят за меня, а мои батареи почти всегда полухолодные, счет тоже 2266 это наверное за весь сезон столько будет.

    P.S. В хургаду так пока и не ездили!!??

    Ответить

    Евгения

    12.01.2021 в 19:34

    Долго мониторила интернет и каким-то образом зашла на этот сайт. Наверное понравился дизайн и информативность, прочитала аргументы установки счетчика, сложила математику и так далее. Спустя некоторе время все-таки решилась и позвонила им для того чтобы оставить заявку. Со мной быстро согласовали дату и время. В назначенный день (вроде уже на следующий день) ко мне приехал мастер по имени Алексей для оформления договора на проведение работ. Примерно через 5-6 дней была сделана полная проектная документация (папка со схемами, чертежами, какими-то формулами и вычислениями), и в тот же день был установлен счетчик и термоголовки на радиаторы. счетчик поставили свой, польский, всю зиму отработал хорошо, сегодня пришла платёжка на тепло за декабрь — около 1100 грн за квартиру в 60+ квадратов, по-моему очень даже неплохо!! Поэтому решила сразу отписаться ))

    Спасибо Водомер-Мастеру и отдельно мастеру Алексею за работу, буду рекомендовать вас!

    Ответить

    Андрей

    19.01.2021 в 22:58

    Неплохо, у меня за такую же квадратуру в сталинке пришел счет 2266 гривень! При том что пол декабря батареи были полумертвые. За январь счет вообще боюсь сколько будет! ?? здесь должен бвть мат

    Ответить

    Жека

    27.01.2021 в 16:38

    Такая же фигня. Только не в сталинке, а панельке. Установка тепловых счетчиков в таких домах возможна тока при полной смене системы труб и коммуникаций в доме. Можно сказать невозможно, кто этим будет заниматься? А так пол дома должников ну ппц

    https://kiev.poverka.net.ua/ustanovka-schetchika-

  141. anndrotak August 21, 2021 at 2:08 am #

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    Во-вторых, если дело дошло до отстранения (об этом работник уведомляется официальным приказом) или представители руководства требуют написать объяснительную, необходимо письменно указать, что вы временно воздерживаетесь от вакцинации и при этом не входите в число тех, кого обязали делать прививку актом региональных властей. Данный аргумент важен, так как, если вас заставляют вакцинироваться просто потому, что так хочет начальник, это незаконно.

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